Pifithrin-β hydrobromide
CAS: 511296-88-1
Ref. TM-T3637
2mg | 40.00 € | ||
5mg | 55.00 € | ||
10mg | 92.00 € | ||
25mg | 147.00 € | ||
50mg | 207.00 € | ||
100mg | 309.00 € | ||
1ml*10 (DMSO) | 57.00 € |
Product Information
- Cyclic PFT-α, PFT-β, Cyclic Pifithrin-α hydrobromide, Pifithrin-β, PFT β (hydrobromide)
Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM).
Chemical properties
Technical inquiry about: TM-T3637 Pifithrin-β hydrobromide
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