MCC950
CAS: 210826-40-7
Ref. TM-T3701
| 2mg | 49.00 € | ||
| 5mg | 57.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 176.00 € | ||
| 50mg | 319.00 € | ||
| 100mg | 567.00 € | ||
| 1ml*10 (DMSO) | 61.00 € |
Product Information
- CP-456773
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and noncanonical NLRP3 activation at nanomolar concentrations. MCC950 specifically inhibited activation of NLRP3 but not the AIM2, NLRC4 or NLRP1 inflammasomes. MCC950 reduced IL-1β production in vivo and attenuated the severity of experimental autoimmune encephalomyelitis (EAE), a disease model of multiple sclerosis.
Chemical properties
Technical inquiry about: TM-T3701 MCC950
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