(±)-Equol

CAS: 94105-90-5

Ref. TM-T4000

Product Information

• Name: (±)-Equol
• Synonyms: Equol, (R,S)-Equol, (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, (?à)-Equol, (S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, 3,4-Dihydro-3-(4-hydroxyphenyl)-(S)-2H-1-benzopyran-7-ol, 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, 3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol, 7,4'-Homoisoflavane, 7,4'-Isoflavandiol, Ccris 9222, NV 07α, NV07a, S-Equol
• CAS: 94105-90-5

Description

(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (±)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). (±)-Equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies.

• Brand: Targetmol

Chemical properties

• Molecular weight: 242.27
• Formula: C₁₅H₁₄O₃
• Purity: 98.28%
• Color/Form: Solid