AG126
CAS: 118409-62-4
Ref. TM-T4092
1mg | 35.00 € | ||
2mg | 51.00 € | ||
5mg | 72.00 € | ||
10mg | 113.00 € | ||
25mg | 218.00 € | ||
50mg | 322.00 € | ||
100mg | 477.00 € | ||
1ml*10 (DMSO) | 77.00 € |
Product Information
- Tyrphostin AG126, AG 126
- Ag 126
- (3-Hydroxy-4-Nitrobenzylidene)Propanedinitrile
AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vivo, attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in diverse animal models. AG-126 weakly inhibits epidermal GFRK (IC50: 450 μM) and platelet-derived GFRK (IC50 >100 μM).
Chemical properties
Technical inquiry about: TM-T4092 AG126
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