Capmatinib 2HCl
CAS: 1197376-85-4
Ref. TM-T4260
1mg | 43.00 € | ||
2mg | 54.00 € | ||
5mg | 69.00 € | ||
10mg | 86.00 € | ||
25mg | 144.00 € | ||
50mg | 252.00 € | ||
100mg | 421.00 € | ||
500mg | 976.00 € | ||
1ml*10 (DMSO) | 95.00 € |
Product Information
- INC-280 2HCl, INCB28060 2HCl
Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, Capmatinib 2HCl potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis in vitro.
Chemical properties
Technical inquiry about: TM-T4260 Capmatinib 2HCl
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