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Capmatinib 2HCl
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Capmatinib 2HCl

CAS: 1197376-85-4

Ref. TM-T4260

1mg
43.00 €
2mg
54.00 €
5mg
69.00 €
10mg
86.00 €
25mg
144.00 €
50mg
252.00 €
100mg
421.00 €
500mg
976.00 €
1ml*10 (DMSO)
95.00 €
Estimated delivery in United States, on Thursday 18 Apr 2024

Product Information

Name:
Capmatinib 2HCl
Synonyms:
  • INC-280 2HCl, INCB28060 2HCl
Description:

Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, Capmatinib 2HCl potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis in vitro.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
485.34
Formula:
C23H19Cl2FN6O
Purity:
100%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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