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Aftin-4
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Aftin-4

CAS: 866893-90-5

Ref. TM-T4364

1mg
48.00 €
2mg
64.00 €
5mg
118.00 €
10mg
183.00 €
25mg
369.00 €
50mg
550.00 €
100mg
783.00 €
1ml*10 (DMSO)
94.00 €
Estimated delivery in United States, on Thursday 18 Apr 2024

Product Information

Name:
Aftin-4
Synonyms:
  • Aftin 4, Aftin4
Description:

Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus, accompanied by learning deficits and mitochondrial ultrastructural changes similar to those found in the brains of patients with AD. Aftin-4(Aftin4) can thus be used to induce a rapid, acute Alzheimer's disease-like toxicity in the rodent brain.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
368.48
Formula:
C20H28N6O
Purity:
99.03%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T4364 Aftin-4

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