Aftin-4
CAS: 866893-90-5
Ref. TM-T4364
1mg | 48.00 € | ||
2mg | 64.00 € | ||
5mg | 118.00 € | ||
10mg | 183.00 € | ||
25mg | 369.00 € | ||
50mg | 550.00 € | ||
100mg | 783.00 € | ||
1ml*10 (DMSO) | 94.00 € |
Product Information
- Aftin 4, Aftin4
Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor. Aftin-4(Aftin4) increased Aβ-1-42, but not Aβ-1-40 in mouse hipppocampus, accompanied by learning deficits and mitochondrial ultrastructural changes similar to those found in the brains of patients with AD. Aftin-4(Aftin4) can thus be used to induce a rapid, acute Alzheimer's disease-like toxicity in the rodent brain.
Chemical properties
Technical inquiry about: TM-T4364 Aftin-4
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