Proguanil hydrochloride
CAS: 637-32-1
Ref. TM-T4382
5mg | 59.00 € | ||
10mg | 70.00 € | ||
25mg | 103.00 € | ||
50mg | 182.00 € | ||
100mg | 321.00 € | ||
200mg | 513.00 € | ||
500mg | 815.00 € | ||
1ml*10 (DMSO) | 69.00 € |
Product Information
- Paludrine hydrochloride, Chlorguanide hydrochloride, Chloroquanil
- 1-(p-Chlorophenyl)-5-isopropylbiguanide hydrochloride
- 1-[N′-(4-Chlorophenyl)carbamimidamido]-N-(propan-2-yl)methanimidamide hydrochloride
- 1-{(1E)-amino[(4-chlorophenyl)amino]methylidene}-2-(1-methylethyl)guanidine hydrochloride
- 3359 Rp
- Biguanide, 1-(p-chlorophenyl)-5-isopropyl-, monohydrochloride
- Chloroguanide hydrochloride
- Chloroquanil
- Diguanyl
- Drinupal
- See more synonyms
- Drinupal hydrochloride
- Guanatol
- Guanatol hydrochloride
- Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-, Hydrochloride (1:1)
- Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N′-(1-methylethyl)-, monohydrochloride
- M 4888
- Paludrine
- Paludrine hydrochloride
- Palusil
- Palusil hydrochloride
- Proguanil HCL
- Rp 3359
- Sn 12,837
- Tirian
- Tirian hydrochloride
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguanil hydrochloride is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.
Chemical properties
Technical inquiry about: TM-T4382 Proguanil hydrochloride
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