Ethacrynic acid

CAS: 58-54-8

Ref. TM-T4564

Product Information

• Name: Ethacrynic acid
• Synonyms: Edecrin, Etacrynic Acid, Hydromedin, (2,3-Dichloro-4-(2-Methylene-1-Oxobutyl)Phenoxy)-Acetic Acid, (4-(2-Methylenebutyryl)-2,3-Dichlorophenoxy)Acetic Acid, 2,3-Dichloro-4-(2-Methylenebutyryl)Phenoxyacetic Acid, 2,3-Dichloro-4-(2-ethyl-1-oxo-2-propenyl)-phenoxyacetic acid, 2-[2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy]acetic acid, 2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid, 4-(2-Methylenebutyryl)Phenoxyacetic Acid, Acetic acid, 2-[2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, Acetic acid, [2,3-dichloro-4-(2-methylene-1-oxobutyl)phenoxy]-, Acetic acid, [2,3-dichloro-4-(2-methylenebutyryl)phenoxy]-, Acide Etacrynique, Acido Etacrinico, Crinuril, Crinuryl, Dethacrynic acid, Edecril, Edecrin, Edecrina, Endecril, Etacrinic Acid, Etacrynic acid, Etacrynsaure, Etakrinic Acid, Ethacrynic, Hidromedin, Hydromedin, Mingit, Mk-595, Nsc 624008, Nsc 85791, Otacril, Redmax, Reomax, Taladren, Uregit, [2,3-Dichloro-4-(2-methylenebutyryl)phenoxy]acetic acid, [[2,3-Dichloro-4-[2-(methylene)butanoyl]phenyl]oxy]acetic acid
• CAS: 58-54-8

Description

Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase and Wnt signalling, producing cytotoxicity in chronic lymphocytic leukaemia cells and other tumour cells.

• Brand: Targetmol

Chemical properties

• Molecular weight: 303.14
• Formula: C₁₃H₁₂Cl₂O₄
• Purity: 99.15%
• Color/Form: Crystals Physical Description White Solid (Ntp 1992)