Balsalazide sodium hydrate

CAS: 150399-21-6

Ref. TM-T4615

Product Information

• Name: Balsalazide sodium hydrate
• Synonyms: Balsalazide disodium dihydrate, Balsalazide disodium salt dihydrate, Balsalazide disodium, (E)-5-[[4-[[(2-CARBOXYETHYL)AMINO]CARBONYL]PHENYL]AZO]-2-HYDROXYBENZOIC ACID, DISODIUM SALT, dihydrate, (E)-5-[[p-[(2-Carboxyethyl)carbamoyl]phenyl]azo]salicylic acid,disodium salt,dihydrate, Balsalazide Disodium 2-Hydrate, Balsalazide disodium hydrate, Balsalazide disodium salt dihydrate, Benzoic acid, 5-[(1E)-2-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]diazenyl]-2-hydroxy-, sodium salt, hydrate (1:2:2), Benzoic acid, 5-[(1E)-[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, disodium salt, dihydrate, Benzoic acid, 5-[[4-[[(2-carboxyethyl)amino]carbonyl]phenyl]azo]-2-hydroxy-, disodium salt, dihydrate, (E)-, disodium (3Z)-3-({4-[(2-carboxylatoethyl)carbamoyl]phenyl}hydrazono)-6-oxocyclohexa-1,4-diene-1-carboxylate dihydrate
• CAS: 150399-21-6

Description

Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug. High dose Balsalazide sodium hydrate(3.0 g twice daily) was superior in maintaining remission in patients with ulcerative colitis compared with a low dose (1.5 g twice daily) or a standard dose of mesalazine (0.5 g three times daily). All three treatments were safe and well tolerated [1]. Balsalazide sodium hydrate is approved for the treatment of mild-to-moderate active UC. It is efficacious for the induction of remission in mild to moderate UC and has a favorable safety profile, with the added advantages of greater efficacy of remission induction and rapidity of onset [2].

• Brand: Targetmol

Chemical properties

• Molecular weight: 437.31
• Formula: C₁₇H₁₇N₃Na₂O₈
• Purity: 99.46%
• Color/Form: Yellow To Orange Crystalline Powder