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SB297006
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SB297006

CAS: 58816-69-6

Ref. TM-T4674

5mg
74.00 €
10mg
99.00 €
25mg
189.00 €
50mg
348.00 €
100mg
515.00 €
1ml*10 (DMSO)
76.00 €
Estimated delivery in United States, on Wednesday 17 Apr 2024

Product Information

Name:
SB297006
Synonyms:
  • SB 297006
Description:

SB297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ. It is at least 250-fold selective for CCR3 over a panel of other chemokine receptors. SB 297006 blocks CCR3-mediated calcium mobilization induced by eotaxin, eotaxin-2, and MCP-4 in transfected cells. It suppresses antigen-induced accumulation of Th2 lymphocytes and eosinophils in lungs of mice when delivered subcutaneously (100 mg/kg).

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
342.35
Formula:
C18H18N2O5
Purity:
98%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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