Tetrahydrocoptisine

CAS: 4312-32-7

Ref. TM-T4S2063

Product Information

• Name: Tetrahydrocoptisine
• Synonyms: STYLOPINE, (RS)-Stylopine, (S)-stylopine, (±)-Stylopine, 2,3:9,10-Bis(methylenedioxy)-13a-berbine, 2,3:9,10-Bis(methylenedioxy)berbine, 4H-Bis[1,3]benzodioxolo[5,6-a:4′,5′-g]quinolizine, 6,7,12b,13-tetrahydro-, 4H-[1,3]benzodioxolo[5,6-a]-1,3-benzodioxolo[4,5-g]quinolizine, 6,7,12b,13-tetrahydro-, 6,7,12b,13-Tetrahydro-4H-bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinolizine, 6,7,12b,13-Tetrahydro-4H-bis[1,3]benzodioxolo[5,6-a:4′,5′-g]quinolizine, 7461-02-1, Berbine, 2,3:9,10-bis(methylenedioxy)-, (±)-, Chelidamine, NSC 110382, NSC 404529, Stylopine (VAN), dl-Stylopine, dl-Tetrahydrocoptisine
• CAS: 4312-32-7

Description

1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. 3. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. 4. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.

• Brand: Targetmol

Chemical properties

• Molecular weight: 323.34
• Formula: C₁₉H₁₇NO₄
• Purity: 99.71%
• Color/Form: Solid