Estimated delivery in United States, on Thursday 13 Mar 2025
Product Information
Name:
ACT001
Description:
ACT001 is an orally active PAI-1 inhibitor by inhibiting the phosphorylation of PI3K and AKT. ACT001 inhibits the phosphorylation of STAT3 and PD-L1 expression by directly binding to STAT3. ACT001, a fumarate salt form of DMAMCL (a prodrug of Micheliolide), can cross the blood-brain barrier. ACT001 has a synergistic effect with cisplatin through the inhibition of the PAI-1/PI3K/AKT pathway. ACT001 has potent anti-glioblastoma (GBM) activity and immunomodulatory effects [1] [2].
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
409.479
Formula:
C21H31NO7
Color/Form:
Soild
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T60102 ACT001
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