(E/Z)-Rigosertib sodium
CAS: 1225497-78-8
Ref. TM-T6070
2mg | 40.00 € | ||
5mg | 60.00 € | ||
10mg | 94.00 € | ||
25mg | 181.00 € | ||
50mg | 339.00 € | ||
100mg | 580.00 € | ||
1ml*10 (DMSO) | 78.00 € |
Product Information
- (E/Z) ON-01910 sodium
ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity.
Chemical properties
Technical inquiry about: TM-T6070 (E/Z)-Rigosertib sodium
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