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Onalespib
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Onalespib

CAS: 912999-49-6

Ref. TM-T6284

1mg
48.00 €
2mg
64.00 €
5mg
87.00 €
10mg
156.00 €
25mg
248.00 €
50mg
353.00 €
100mg
522.00 €
500mg
1,142.00 €
1ml*10 (DMSO)
87.00 €
Estimated delivery in United States, on Wednesday 17 Apr 2024

Product Information

Name:
Onalespib
Synonyms:
  • AT13387, Onalespib (AT13387)
  • (2,4-Dihydroxy-5-isopropylphenyl)[5-[(4-methylpiperazin-1-yl)methyl]-1,3-dihydroisoindol-2-yl]methanone
  • (2,4-Dihydroxy-5-propan-2-ylphenyl)-[5-[(4-methylpiperazin-1-yl)methyl]-1,3-dihydroisoindol-2-yl]methanone
  • 1H-Isoindole, 2-[2,4-dihydroxy-5-(1-methylethyl)benzoyl]-2,3-dihydro-5-[(4-methyl-1-piperazinyl)methyl]-
  • At 13387X
  • At-13387
  • Ati 3387
  • Methanone, [1,3-dihydro-5-[(4-methyl-1-piperazinyl)methyl]-2H-isoindol-2-yl][2,4-dihydroxy-5-(1-methylethyl)phenyl]-
  • [1,3-Dihydro-5-[(4-methyl-1-piperazinyl)methyl]-2H-isoindol-2-yl][2,4-dihydroxy-5-(1-methylethyl)phenyl]methanone
Description:

Onalespib (AT13387) is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Onalespib selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Hsp90, a chaperone protein upregulated in a variety of tumor cells, regulates the folding, stability and degradation of many oncogenic signaling proteins.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
409.52
Formula:
C24H31N3O3
Purity:
99.82%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T6284 Onalespib

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