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Buclizine dihydrochloride
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Buclizine dihydrochloride

CAS: 129-74-8

Ref. TM-T6426

50mg
35.00 €
100mg
49.00 €
200mg
59.00 €
1ml*10 (DMSO)
49.00 €
Estimated delivery in United States, on Wednesday 17 Apr 2024

Product Information

Name:
Buclizine dihydrochloride
Synonyms:
  • Longifene, Buclina, Buclizine HCl, UCB-4445
  • 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride
  • 1-(4-Tert-Butylbenzyl)-4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazine Dihydrochloride
  • 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)diethylenediamine hydrochloride
  • 1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride
  • 1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride
  • Aphilan R
  • Bucladin S
  • Buclina
  • Buclizine HCl
  • See more synonyms
  • Buclizine Hydrochloride
  • Buclodin
  • Histabutyzine hydrochloride
  • Longifene
  • NSC 25141
  • Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-α-phenylbenzyl)-, dihydrochloride
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2)
  • Softran
  • Ucb 4445
  • Vibazine
  • Vibazine Hydrochloride
Description:

Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine dihydrochloride exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemoreceptor trigger zone (CTZ) and may reduce nausea and vomiting.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
505.95
Formula:
C28H33ClN2·2HCl
Purity:
99.56%
Color/Form:
Off-White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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