Buclizine dihydrochloride
CAS: 129-74-8
Ref. TM-T6426
50mg | 35.00 € | ||
100mg | 49.00 € | ||
200mg | 59.00 € | ||
1ml*10 (DMSO) | 49.00 € |
Product Information
- Longifene, Buclina, Buclizine HCl, UCB-4445
- 1-(4-(tert-Butyl)benzyl)-4-((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride
- 1-(4-Tert-Butylbenzyl)-4-[(4-Chlorophenyl)(Phenyl)Methyl]Piperazine Dihydrochloride
- 1-(p-Chlorobenzhydryl)-4-(p-tert-butylbenzyl)diethylenediamine hydrochloride
- 1-(p-tert-Butylbenzyl)-4-(p-chlorodiphenylmethyl)piperazine dihydrochloride
- 1-p-Chlorobenzhydryl-4-p-(t)-butylbenzylpiperazine dihydrochloride
- Aphilan R
- Bucladin S
- Buclina
- Buclizine HCl
- See more synonyms
- Buclizine Hydrochloride
- Buclodin
- Histabutyzine hydrochloride
- Longifene
- NSC 25141
- Piperazine, 1-(p-tert-butylbenzyl)-4-(p-chloro-α-phenylbenzyl)-, dihydrochloride
- Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, dihydrochloride
- Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-, hydrochloride (1:2)
- Softran
- Ucb 4445
- Vibazine
- Vibazine Hydrochloride
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine dihydrochloride exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemoreceptor trigger zone (CTZ) and may reduce nausea and vomiting.
Chemical properties
Technical inquiry about: TM-T6426 Buclizine dihydrochloride
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