Dovitinib lactate hydrate
CAS: 915769-50-5
Ref. TM-T6479
5mg | 54.00 € | ||
10mg | 82.00 € | ||
25mg | 138.00 € | ||
50mg | 226.00 € | ||
100mg | 378.00 € | ||
200mg | 551.00 € | ||
1ml*10 (DMSO) | 54.00 € |
Product Information
- Dovitinib (TKI258) Lactate, Dovitinib Lactate, TKI258
- 4-Amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone 2-hydroxypropanoate hydrate (1:1:1)
- 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one
Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
Chemical properties
Technical inquiry about: TM-T6479 Dovitinib lactate hydrate
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