Rhynchophylline

CAS: 76-66-4

Ref. TM-T6S0659

Product Information

• Name: Rhynchophylline
• Synonyms: Rhynchophyllin, Rhyncophylline, Mitrinermine, Mitrinermin, Corynoxan-16-carboxylic acid, 16,17-didehydro-17-methoxy-2-oxo-, methyl ester, (7β,16E,20α)-, Mitrinermin, Mitrinermine, NSC 21731, Rhyncholphylline, Rhynchophyllin, Rhyncophylline, Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1′R,6′R,7′S,8′aS)-, Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1′R-[1′α,6′β,7′α(E),8′aβ]]-, methyl (16Z)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (3xi,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (3xi,16Z,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate, methyl (7beta,16E,20alpha)-16-(methoxymethylidene)-2-oxocorynoxan-17-oate
• CAS: 76-66-4

Description

1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in cultured neurons in vitro. 3. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia.

• Brand: Targetmol

Chemical properties

• Molecular weight: 384.47
• Formula: C₂₂H₂₈N₂O₄
• Purity: 99.44%
• Color/Form: Red Brown Or White Fine Powder