Product Information
Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
Synonyms:
- 11β-13,14-dihydro-15-keto PGF2α
Brand:Targetmol
Description:11β-13,14-Dihydro-15-keto PGF2α, a PGD2 metabolite in the 15-hydroxy PGDH pathway, is formed in human males upon infusion or inhalation of tritiated PGD2, with peak plasma levels of both 11β-PGF2α and 11β-13,14-dihydro-15-keto PGF2α observed within 10 minutes. In human lung homogenates, PGD2 is metabolized firstly to 11β-PGF2α and subsequently to 11β-15-keto-PGF2α in the presence of NAD+, but not to 11β-13,14-dihydro-15-keto PGF2α. Conversely, guinea pig liver and kidney homogenates can metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α via 11β-PGF2α, with both NAD+ and NADP+ being requisite for this conversion.
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Chemical properties
Molecular weight:354.5
Formula:C20H34O5
Color/Form:Solid
Technical inquiry about: 11β-13,14-dihydro-15-keto Prostaglandin F2α
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