PRO-6E

CAS: 2353493-69-1

Ref. TM-T84709

Product Information

• Name: PRO-6E
• Brand: Targetmol
• Description: PRO-6E is an orally active, Cereblon ligand-based PROTAC that promotes MET degradation, achieving up to 81.9% effectiveness at a concentration of 1 μM in MKN-45 cells. It demonstrates tumor growth inhibition both in vivo and in vitro, alongside inducing cell apoptosis and cell cycle arrest.

Chemical properties

• Molecular weight: 848.75
• Formula: C₄₂H₄₄Cl₂FN₇O₇
• Color/Form: Solid