SKI-178
CAS: 1259484-97-3
Ref. TM-T9014
| 2mg | 48.00 € | ||
| 5mg | 71.00 € | ||
| 10mg | 112.00 € | ||
| 25mg | 212.00 € | ||
| 50mg | 337.00 € | ||
| 100mg | 508.00 € | ||
| 500mg | 1,091.00 € | ||
| 1ml*10 (DMSO) | 79.00 € |
Estimated delivery in United States, on Thursday 9 May 2024
Product Information
Name:
SKI-178
Synonyms:
- SKI178
CAS:
Description:
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
394.42
Formula:
C21H22N4O4
Purity:
99.2%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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