Isotetrandrine

CAS: 477-57-6

Ref. TM-TN1806

Product Information

• Name: Isotetrandrine
• Synonyms: (1Beta,1'Beta)-6,6',7,12-Tetramethoxy-2,2'-Dimethylberbaman, (4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, (R,S)-Tetrandrine, 1-Isotetrandrine, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aR)-, 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, [4aS-(4aR*,16aS*)]-, 6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman, 8,19,20,25-Tetramethoxy-14,30-Dimethyl-6,22-Dioxa-14,30-Diazaheptacyclo[22.6.2.2~2,5~.1~7,11~.1~13,17~.0~21,33~.0~27,31~]Hexatriaconta-2,4,7(34),8,10,17(33),18,20,24,26,31,35-Dodecaene (Non-Preferred Name), Berbaman, 6,6',7,12-tetramethoxy-2,2'-dimethyl- (9CI), Berbaman, 6,6′,7,12-tetramethoxy-2,2′-dimethyl-, Ccris 6540, Isosinomenin A, Isosinomenine A, Nsc 97338, O,O'-Dimethylobamegine, O,O'-Dimethylstepholine, O-Methylberbamine
• CAS: 477-57-6

Description

Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue oxidative injury and pulmonary inflammatory process.

• Brand: Targetmol

Chemical properties

• Molecular weight: 622.75
• Formula: C₃₈H₄₂N₂O₆
• Purity: 98%
• Color/Form: Solid