TRV-120027 TFA
Ref. TM-TP2158
1mg | 69.00 € | ||
5mg | 184.00 € | ||
10mg | 293.00 € | ||
25mg | 503.00 € | ||
50mg | 726.00 € | ||
100mg | 993.00 € | ||
1ml*10 (DMSO) | 334.00 € |
Product Information
- TRV-120027 TFA (1234510-46-3 free base)
TRV-120027 TFA is an angiotensin II-mediated vasoconstriction inhibitor and increases cardiomyocyte contractility. TRV-120027 TFA is a β-arrestin-1-biased AT1R agonist engaging ß-arrestins while blocking G-protein signaling[1]. TRV-120027 TFA induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling and promotes the formation of a macromolecular complex composed of AT1R-β-arrestin-1-TRPC3-PLCγ at the plasma membrane.
Chemical properties
Technical inquiry about: TM-TP2158 TRV-120027 TFA
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