Estimated delivery in United States, on Tuesday 14 May 2024
Product Information
Name:
(R)-Ambrisentan
Controlled Product
Synonyms:
- Benzenepropanoic acid
- α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-
- (αR)-
- (αR)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid
- Ambrisentan related
- 3109.Z
CAS:
Description:
Applications (R)-Ambrisentan is the R-isomer impurity of Ambrisentan (A575860), which is a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996); Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002); Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003);
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
378.42
Formula:
C22H22N2O4
Color/Form:
White to Off-White Solid
InChI:
InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m0/s1
InChI key:
InChIKey=OUJTZYPIHDYQMC-IBGZPJMESA-N
SMILES:
COC(c1ccccc1)(c1ccccc1)[C@@H](Oc1nc(C)cc(C)n1)C(=O)O
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-A575873 (R)-Ambrisentan
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