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N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester-d3
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N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester-d3

CAS: 1013330-79-4

Ref. TR-A601632

Estimated delivery in United States, on Friday 18 Dec 2020

Product Information

Name:
N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester-d3
Description:

Applications N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester-d3 is the labelled analog of a biaryl benzamides that exhibit inhibitory selectivity over class II Histone Deacetylase (HDACs) and as well as class I HDACs. N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester was deteremined to be a potent and selective inhibitor of HDAC with reduced off-target activity and tumor growth inhibition activity.
References Witter, D.J., et al.: Bioorg. Medn. Chem. Letters., 18, 726 (2008);

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Chemical properties

Molecular weight:
378.44
Formula:
C22H18D3N3O3
Color/Form:
White Solid
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Hazard Info

UN Number:
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