7-Aminocephalosporanic Acid

CAS: 957-68-6

Ref. TR-A603415

Product Information

• Name: 7-Aminocephalosporanic Acid
• Synonyms: Cefazolin Sodium Imp. H (EP), Cefazolin Imp. H (EP), Cefoperazone Sodium Imp. E (EP), Cefoperazone Imp. E (EP), (6R,7R)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, 7-ACA, 7-ACA, Cephalexin related, Cefalotin Sodium Impurity C, Cefazolin Sodium Impurity H, Cefoperazone Sodium Impurity E, Cefalotin Impurity C, Cefazolin Impurity H, Cefoperazone Impurity E, (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R-trans)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (7R)-7-Aminocephalosporanic acid, 3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(Acetoxymethyl)-7-aminocephem-4-carboxylic acid, 3-Acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid, 3-Acetoxymethyl-7β-aminoceph-3-em-4-carboxylic acid, 3-Acetoxymethylen-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 3-Acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsaure, 3-[(Acetyloxy)Methyl]-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R-trans)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, acetate (ester), 7-Aca, 7-Acs, 7-Amino Cephalosporanic Acid, 7-Amino-3-acetoxymethyl-3-cephem-4-carboxylic acid, 7-Amino-3-acetoxymethyl-Δ-3-cephem-4-carboxylic acid, 7-Amino-3-acetoxymethyl-Δ3-cephem-4-carboxylic acid, 7-Amino-3-acetoxymethyl-Δ³-cephem-4-carboxylic acid, 7β-Amino-3-acetoxymethylcephemcarboxylic acid, 7β-Aminocephalosporanic acid, Acide 3-Acetoxymethylene-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylique, Acido 3-Acetoximetilen-7-Amino-8-Oxo-5-Tia-1-Azabiciclo[4.2.0]Oct-2-Eno-2-Carboxilico

Description

Impurity Cefoperazone EP Impurity E
Stability Hygroscopic
Applications 7-Aminocephalosporanic Acid (Cefoperazone EP Impurity E) is the starting material for semi-synthetic cephalosporins. Obtained by mild acid hydrolysis of cephalosporin C.
References Matsuda, A., et al.: J. Bacteriol., 169, 5815 (1987), Aramori, I., et al.: J. Ferment. Bioeng., 72, 227 (1991), Park, S., et al.: J. Biosci. Bioeng., 94, 218 (2002), Takimoto, A., et al.: Appl. Microbiol. Biotechnol., 65, 263 (2004),

• Brand: TRC

Chemical properties

• Molecular weight: 272.28
• Formula: C₁₀H₁₂N₂O₅S
• Color/Form: White To Light Yellow
• InChI: InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1
• InChI key: InChIKey=HSHGZXNAXBPPDL-HZGVNTEJSA-N
• SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1