7-Amino-3 chloromethyl-3-cephem-4-carboxylic Acid p-Methoxybenzyl Ester Hydrochloride

CAS: 113479-65-5

Ref. TR-A603445

Product Information

• Name: 7-Amino-3 chloromethyl-3-cephem-4-carboxylic Acid p-Methoxybenzyl Ester Hydrochloride
• Synonyms: (6R,7R)-7-Amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (4-Methoxyphenyl)methyl Ester Hydrochloride, 4-Methoxybenzyl 7β-amino-3-(chloromethyl)-3-cephem-4-carboxylate hydrochloride, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(chloromethyl)-8-oxo-, (4-methoxyphenyl)methyl ester, hydrochloride (1:1), (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(chloromethyl)-8-oxo-, (4-methoxyphenyl)methyl ester, monohydrochloride, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(chloromethyl)-8-oxo-, (4-methoxyphenyl)methyl ester, monohydrochloride, (6R-trans)-, 7-Amino-3-chloromethyl-3-cephem-4-carboxylic acid p-methoxybenzyl ester, hydrochloride, Acle Hcl, p-Methoxybenzyl 7β-amino-3-(chloromethyl)-3-cephem-4-carboxylate hydrochloride
• CAS: 113479-65-5

Description

Stability Hygroscopic
Applications Cefazolin intermediate as antibacterials.
References Brown, R., et al.: J. Med. Chem., 33, 2114 (1990), Minnick, A., et al.: J. Antimicrob. Agents Chemother., 36, 840 (1992), Tsuji, K., et al.: Bioorg. Med. Chem., 4, 2135 (1996), Kinzel, O., et al.: J. Antibiot., 51, 499 (1998),

• Brand: TRC

Chemical properties

• Molecular weight: 405.30
• Formula: C₁₆H₁₈Cl₂N₂O₄S
• Color/Form: Off-White to Light Beige Solid
• InChI: 1H/t12-,15-, InChI=1S/C16H17ClN2O4S.ClH/c1-22-11-4-2-9(3-5-11)7-23-16(21)13-10(6-17)8-24-15-12(18)14(20)19(13)15, /h2-5,12,15H,6-8,18H2,1H3, /m1./s1
• InChI key: InChIKey=LYIIGHOYDRRHAJ-XRZFDKQNSA-N
• SMILES: COc1ccc(COC(=O)C2=C(CCl)CS[C@@H]3[C@H](N)C(=O)N23)cc1.Cl