Product Information
Name:Des-(4-(dimethylamino)-2-butenoyl)-Neratinib
Controlled Product
Synonyms:
- 6-Amino-4-[3-Chloro-4-[(2-pyridinyl)methoxy]anilino]-3-cyano-7-ethoxyquinoline,6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile
- 4-[4-[(2-Pyridyl)methoxy]-3-chloroanilino]-6-amino-3-cyano-7-ethoxyquinoline
Brand:TRC
Description:Applications 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, is used in the synthetic preparation of aminopropanamides which is used in irreversible inhibition of epidermal growth factor receptor (EGFR) for potential use in cancer therapy.References Carmi, C., et al.: J. Med. Chem., 55, 2251 (2012)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:445.9
Formula:C24H20ClN5O2
Color/Form:Neat
InChI:InChI=1S/C24H20ClN5O2/c1-2-31-23-11-21-18(10-20(23)27)24(15(12-26)13-29-21)30-16-6-7-22(19(25)9-16)32-14-17-5-3-4-8-28-17/h3-11,13H,2,14,27H2,1H3,(H,29,30)
InChI key:InChIKey=DIVNUTGTTIRPQA-UHFFFAOYSA-N
SMILES:COc1ccc(CN)cc1OC
Technical inquiry about: Des-(4-(dimethylamino)-2-butenoyl)-Neratinib
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