2-Aminoethyl Methanethiosulfonate Hydrochloride

CAS: 37597-96-9

Ref. TR-A609150

Product Information

• Name: 2-Aminoethyl Methanethiosulfonate Hydrochloride
• Synonyms: 2-methylsulfonylsulfanylethanamine;hydrochloride

Description

Stability Moisture sensitive
Applications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. Useful for mapping the pore-lining regions of the ryanodine receptor.
References Xu, M. & Akabus, M.H.: J. Biol. Chem., 268, 21505 (1993), Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996); Frillingos, S., & Kaback, H.R.: Biochem., 35, 3950 - 3956 (1996)

• Brand: TRC

Chemical properties

• Molecular weight: 191.70
• Formula: C₃H₉NO₂S₂·ClH
• Color/Form: Neat
• InChI: InChI=1S/C3H9NO2S2.ClH/c1-8(5,6)7-3-2-4;/h2-4H2,1H3;1H
• InChI key: InChIKey=NRPKIYSDVDLOTO-UHFFFAOYSA-N
• SMILES: CS(=O)(=S)OCCN.Cl