Product Information
Name:
Amonafide
Synonyms:
- 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
- FA 142
- M-FA 142
- MADE-FA 142
- NCI 308847
- NSC 308847
- Nafidimide
- 1H-Benz[de]isoquinoline-1,3(2H)-dione, 5-amino-2-[2-(dimethylamino)ethyl]-
- 5-amino-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione
- Benzisoquinolinedione
- See more synonyms
- Fa 142
- M-Fa 142
- Made-Fa 142
- Nci 308847
Description:
Applications Amonafide is a DNA intercalator and topoisomerase II inhibitor in clinical development for the treatment of neoplastic diseases. Antitumor agent.
References Hsiang, Y., et al.: Mol. Pharmacol., 36, 371 (1989), Costanza, M., et al.: Clin. Cancer Res., 1, 699 (1995), Innocenti, F., et al.: Drug Metab. Dispos., 29, 596 (2001), Brana, M., et al.: J. Med. Chem., 47, 1391 (2004),
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
283.33
Formula:
C16H17N3O2
Color/Form:
Yellow to Dark Yellow Solid
InChI:
InChI=1S/C16H17N3O2/c1-18(2)6-7-19-15(20)12-5-3-4-10-8-11(17)9-13(14(10)12)16(19)21/h3-5,8-9H,6-7,17H2,1-2H3
InChI key:
InChIKey=UPALIKSFLSVKIS-UHFFFAOYSA-N
SMILES:
CN(C)CCN1C(=O)c2cccc3cc(N)cc(c23)C1=O
MDL:
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HS code:
