Z-L-Arginine

CAS: 1234-35-1

Ref. TR-A769400

Product Information

• Name: Z-L-Arginine
• Synonyms: N2-Carboxy-L-arginine N2-Benzyl Ester, N2-Carboxy-L-arginine N-Benzyl Ester, Benzyloxycarbonyl-L-arginine, N-Carbobenzoxyarginine, N2-Benzyloxycarbonyl-L-arginine, Nalpha-(Benzyloxycarbonyl)arginine, (2S)-2-[[(Benzyloxy)carbonyl]amino]-5-carbamimidamidopentanoic acid, (2S)-5-(Diaminomethylideneazaniumyl)-2-(phenylmethoxycarbonylamino)pentanoate, <span class="text-smallcaps">L</span>-Arginine, N²-[(phenylmethoxy)carbonyl]-, <span class="text-smallcaps">L</span>-Arginine, N²-carboxy-, N-benzyl ester, Arginine, N²-carboxy-, N-benzyl ester, Arginine, N²-carboxy-, N²-benzyl ester, <span class="text-smallcaps">L</span>-, Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-arginine, BenzyloxycarbonylLarginine, Cbz-L-arginine, N(alpha)-Benzyloxycarbonyl-L-arginine~Z-Arg-OH, N(alpha)-Cbz-L-arginine, N(alpha)-Z-L-arginine, N-2-carbobenzyloxy-L-arginine, N²-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-arginine, N²-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-arginine, N^α-(Benzyloxycarbonyl)arginine, NALPHA-Benzyloxycarbonyl-L-arginine, Na-Benzyloxycarbonyl-L-arginine, Nalpha-CBZ-L-Arginine, N~2~-[(benzyloxy)carbonyl]-N~5~-(diaminomethylidene)-L-ornithine, Z-Arg, Z-Arg-OH, Z-L-Arg-OH, na-cbz-L-arginine free acid
• CAS: 1234-35-1

Description

Applications Z-L-Arginine is used in the synthesis of renin inhibitors containing phosphorous acid derivatives at the scissile bond. Also used in the synthesis of a peptide deformylase inhibitor BB-3497.
References Allen, M. et al.: J. Med. Chem., 32, 1652 (1989); Davies, S. et al.: Bioorg. Med. Chem. Lett., 13, 2715 (2003);

• Brand: TRC

Chemical properties

• Molecular weight: 308.33
• Formula: C₁₄H₂₀N₄O₄
• Color/Form: White Solid
• InChI: InChI=1S/C14H20N4O4/c15-13(16)17-8-4-7-11(12(19)20)18-14(21)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,18,21)(H,19,20)(H4,15,16,17)/t11-/m0/s1
• InChI key: InChIKey=SJSSFUMSAFMFNM-NSHDSACASA-N
• SMILES: N=C(N)NCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O