Bisindolylmaleimide III Hydrochloride

CAS: 683775-59-9

Ref. TR-B448480

Product Information

• Name: Bisindolylmaleimide III Hydrochloride
• Synonyms: 3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione Hydrochloride

Description

Applications Bisindolylmaleimide III Hydrochloride is a protein kinase C inhibitor and was also shown to exhibit inhibitory activities towards PDK1, an important kinase in the insulin signaling pathway.
References Jena, N.R., et al.: J. Molec. Model., 18, 631 (2012); Murphy, R.C., et al.: ACS. Med. Chem. Lett., 1, 331 (2010);

• Brand: TRC

Chemical properties

• Molecular weight: 384.43 + (36.46)
• Formula: C₂₃H₂₀N₄O₂•(HCl)
• Color/Form: Dark Red Solid
• InChI: InChI=1S/C23H20N4O2.ClH/c24-10-5-11-27-13-17(15-7-2-4-9-19(15)27)21-20(22(28)26-23(21)29)16-12-25-18-8-3-1-6-14(16)18;/h1-4,6-9,12-13,25H,5,10-11,24H2,(H,26,28,29);1H
• InChI key: InChIKey=NXIKRXJEVAWDAX-UHFFFAOYSA-N
• SMILES: Cl.NCCCn1cc(C2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)c2ccccc21