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5-[Bis(methylthio)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione
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5-[Bis(methylthio)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione

CAS: 100981-05-3

Ref. TR-B485958

Estimated delivery in United States, on Monday 14 Dec 2020

Product Information

Name:
5-[Bis(methylthio)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione
Synonyms:
  • 5-[Bis(methylsulfanyl)methylene]-2,2-dimethyl-[1,3]dioxan-4,6-dione
  • 5-[Bis(methylsulfanyl)methylene]-2,2-dimethyl-[1,3]dioxane-4,6-dione
  • Isopropylidene [Bis(methylthio)methylene]malonate
  • Bis(Methylthio)Methylene Meldrums Acid
  • Thioketal
Description:

Stability Moisture Sensitive
Applications 5-[Bis(methylthio)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione is a derivative of Meldrums Acid (M215250), which is an antimicrobial agent. 5-[Bis(methylthio)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione is a synthetic intermediate in the preparation of TGX 115 phosphoinositide 3-kinase inhibitor.
References Nelson, N., et al.: J. Biol. Chem., 245, 143 (1970); Kawamura, M., et al.: Plant Cell Physiol., 21, 745 (1980); Oettmeier, W., et al.: Biochim. Biophys Acta, 890, 260 (1987); Knight, Z., et al.: Bioorg. Med. Chem., 12, 4749 (2004);

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Chemical properties

Molecular weight:
248.32
Formula:
C9H12O4S2
Color/Form:
Yellow to Dark Yellow Solid
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Hazard Info

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