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BMS 754807
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BMS 754807

CAS: 1001350-96-4

Ref. TR-B596315

Estimated delivery in United States, on Monday 21 Dec 2020

Product Information

Name:
BMS 754807
Synonyms:
  • (2S)-1-[4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl]-N-(6-fluoro-3-pyridinyl)-2-methyl-2-pyrrolidinecarboxamide
Description:

Applications BMS 754807 is an inhibitor of insulin-like growth factor 1 receptor (IGF-1R) . It inhibits cell proliferation or induces apoptosis in a variety of cancer cells in vitro. It also inhibits the growth of tumor xenografts in mice. Potent IGF-1R inhibitor.
References Carboni, J., et al.: Mol. Cancer Ther., 8, 3341 (2009); Awasthi, N., et al.: Mol. Cancer Ther., 11, 2644 (2012); Dayyani, F., et al.: PLoS One, 7, 1 (2012)

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Chemical properties

Molecular weight:
461.49
Formula:
C23H24FN9O
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Hazard Info

UN Number:
EQ:
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LQ:

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