Buprenorphine-d4 Hydrochloride

CAS: 53152-21-9

Ref. TR-B689573

Product Information

• Name: Buprenorphine-d4 Hydrochloride
• Synonyms: [5α,7α(S)]-17-(Cyclopropyl-d2-methyl-d2)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol Hydrochloride, CL-112302-d4, NIH-8805-d4, UM-952-d4, Buprenex-d4, Lepetan-d4, Buprenorphine-D4 HCl, (2S)-2-[(-)-(5R,6R,7R,14S)-9α-tetradeuterocyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6-methoxymorphinan-7-yl]- 3,3-dimethylbutan-2-ol hydrochloride, (5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol hydrochloride, (5alpha,7alpha(S))-alpha-tert-Butyl-17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol hydrochloride, 21-Cyclopropyl-7alpha-((S)-1-hydroxy-1,2,2-trimethylpropyl)-6,14-endo-ethano-6,7,8,14-tetrahydrooripavine hydrochloride, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, hydrochloride, (5alpha,7alpha(S))-, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, hydrochloride (1:1), (αS,5α,7α)-, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, hydrochloride, (αS,5α,7α)-, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-, hydrochloride, [5α,7α(S)]-, Buprederm, Buprenex, Buprenorphine HCl, Buprenorphine hydrochloride [USAN:JAN], Buprex, Cl 112,302, DEA No. 9064, Finibron, Lepetan, M 6029, Mr 56, Nih 8805, Rx 6029-M, Sixmo, Subutex, Temgesic, Um 952, Unii-56W8Mw3En1, Vetergesic
• CAS: 53152-21-9

Description

Applications Buprenorphine-d4 Hydrochloride, is the labeled analogue of Buprenorphine (B689570), an Analgesic that demonstrates narcotic agonist-antagonist properties.
References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976), Rance, M.J., Biochem. Pharmacol., 25, 735 (1976), Heel, R.C., et al.: Drugs, 17, 81 (1979),

• Brand: TRC

Chemical properties

• Molecular weight: 508.13
• Formula: C₂₉H₃₈D₄ClNO₄
• Color/Form: White to Pale Yellow Solid
• InChI: InChI=1S/C29H41NO4.ClH/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28, /h8-9,17,20-21,24,31-32H,6-7,10-16H2,1-5H3, /m1./s1/i6D2,7D2, 1H/t20-,21-,24-,26+,27-,28+,29-
• InChI key: InChIKey=UAIXRPCCYXNJMQ-BUBGYZEZSA-N
• SMILES: Cl.[2H]C1([2H])CC1C([2H])([2H])N1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@]2(OC)CC[C@@]3(C[C@@H]2C(C)(O)C(C)(C)C)[C@H]1C5