Product Information
Name:2-tert-Butyldimethylsilyloxyethyl Tosylate
Controlled Product
Synonyms:
- 1-(4-Methylbenzenesulfonate) 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethanol
- 4-Methylbenzenesulfonate 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethanol
Brand:TRC
Description:Applications 2-tert-Butyldimethylsilyloxyethyl Tosylate is an intermediate in the synthesis of Everolimus (E945400), which is Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:330.515
Formula:C15H26O4SSi
Color/Form:Neat
InChI:InChI=1S/C15H26O4SSi/c1-13-7-9-14(10-8-13)20(16,17)18-11-12-19-21(5,6)15(2,3)4/h7-10H,11-12H2,1-6H3
InChI key:InChIKey=SURVAMFPFPDSHK-UHFFFAOYSA-N
SMILES:Cc1ccc(S(=O)(=O)OCCO[Si](C)(C)C(C)(C)C)cc1
Technical inquiry about: 2-tert-Butyldimethylsilyloxyethyl Tosylate
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