9-Carboxymethoxymethylguanine-13C2,15N

CAS: 80685-22-9

Ref. TR-C179992

Product Information

• Name: 9-Carboxymethoxymethylguanine-13C2,15N
• Synonyms: 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]acetic Acid-13C2,15N, Acyclovir Acid-13C2,15N, CMMG-13C2,15N

Description

Stability Hygroscopic
Applications 9-Carboxymethoxymethylguanine-13C2,15N is the labelled analog of 9-Carboxymethoxymethylguanine (C179990) which is a metabolite of Acyclovir (A192400-an antiviral, orally active acyclic nucleoside with inhibitory activity towards several herpes viruses).
References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992); Gunness, P., et al.: Transl. Res., 158, 290 (2011);

• Brand: TRC

Chemical properties

• Molecular weight: 242.167
• Formula: C₂C₆H₉NN₄O₄
• Color/Form: Light Beige Solid
• InChI: InChI=1S/C8H9N5O4/c9-8-11-6-5(7(16)12-8)10-2-13(6)3-17-1-4(14)15/h2H,1,3H2,(H,14,15)(H3,9,11,12,16)/i5+1,6+1,10+1
• InChI key: InChIKey=MICNQLKUSOVNNG-VZQINMRGSA-N
• SMILES: Nc1nc(=O)[13c]2[15n]cn(COCC(=O)O)[13c]2[nH]1