(2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne
CAS: 635708-74-6
Ref. TR-C367610
| 10mg | 308.00 € | ||
| 100mg | 2,019.00 € |
Product Information
Applications (2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne is a byproduct in the synthesis of Terbinafine Hydrochloride (T107500); an orally active, antimycotic allylamine related to Naftifine. It is a specific inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Also antifungal.
References Kazakov, P.V., et al.: Pharm. Chem. J., 40, 452 (2006); Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999)
Chemical properties
Technical inquiry about: TR-C367610 (2Z)-1-Chloro-6,6-dimethyl-2-hepten-4-yne
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