2-Chloro-9-methyl-6-(benzylamino)purine-d3

CAS: 101622-53-1

Ref. TR-C368862

Product Information

• Name: 2-Chloro-9-methyl-6-(benzylamino)purine-d3
• Synonyms: 6-(Benzylamino)-2-chloro-9-methylpurine-d3, 2-Chloro-6-benzylamino-9-methylpurine-d3, 2-Chloro-9-methyl-N-(phenylmethyl)-9H-purin-6-amine-d3, 2-Chloro-6-benzylamino-9-methylpurine, 2-Chloro-9-methyl-6-(benzylamino)purine, 2-Chloro-9-methyl-N-(phenylmethyl)-9H-purin-6-amine, 6-(Benzylamino)-2-chloro-9-methylpurine, 9H-purin-6-amine, 2-chloro-9-methyl-N-(phenylmethyl)-, N-benzyl-2-chloro-9-methyl-9H-purin-6-amine

Description

Applications 2-Chloro-9-methyl-6-(benzylamino)purine-d3 is an isotope labelled intermediate in the synthesis of Olomoucine (O567000), a purine derivative which inhibits cyclin-dependent kinases and induces G1 arrest.
References Liang, M., et al.: Med. Chem. Lett., 3, 985 (2012); Havlicek, L., et al.: J. Med. Chem., 40, 408 (1997); Gonazalez, M.P., et al.: Bull. Math. Biol., 68, 735 (2006); Parker, C. W., et al.: Phytochem., 25, 303 (1986);

• Brand: TRC

Chemical properties

• Molecular weight: 276.74
• Formula: C₁₃H₉D₃ClN₅
• Color/Form: Neat
• InChI: InChI=1S/C13H12ClN5/c1-19-8-16-10-11(17-13(14)18-12(10)19)15-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,15,17,18)/i1D3
• InChI key: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#Cc1cccc(N)c1