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4-Cyanopyridine
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4-Cyanopyridine

CAS: 100-48-1

Ref. TR-C982225

Estimated delivery in United States, on Friday 11 Dec 2020

Product Information

Name:
4-Cyanopyridine
Synonyms:
  • Isonicotinonitrile
  • 4-Azabenzonitrile
  • 4-Pyridinenitrile
  • 4-Pyridyl Cyanide
  • 4-Pyridylcarbonitrile
  • Isonicotinic Acid Nitrile
  • NSC 60681
  • γ-Cyanopyridine
  • Pyridine-4-carbonitrile
  • 4-Pyridinecarbonitrile
  • See more synonyms
  • 4-cyano Pyridine
  • Pyridine-3-Carbonitrile
  • 4-Pyridyl cyanide
  • Isonicotinic acid nitrile
  • Isonicotinonitril
  • Isonicotinonitrilo
  • Nsc 60681
  • Pyridine, 4-Cyano-
Description:

Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.
References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)

Long term storage:
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Chemical properties

Molecular weight:
104.11
Formula:
C6H4N2
Color/Form:
Off-White Solid
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Hazard Info

UN Number:
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