(2-Cyclobuten-1-yldimethylsilyl)benzene

CAS: 847158-86-5

Ref. TR-C990233

Product Information

• Name: (2-Cyclobuten-1-yldimethylsilyl)benzene
• Synonyms: (2-Cyclobuten-1-yldimethylsilyl)-benzene

Description

Applications (2-Cyclobuten-1-yldimethylsilyl)benzene is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

• Brand: TRC

Chemical properties

• Molecular weight: 188.34
• Formula: C₁₂H₁₆Si
• Color/Form: Neat
• InChI: InChI=1S/C12H16Si/c1-13(2,12-9-6-10-12)11-7-4-3-5-8-11/h3-9,12H,10H2,1-2H3
• InChI key: InChIKey=ZXYIXPUTEKMRFP-UHFFFAOYSA-N
• SMILES: C[Si](C)(c1ccccc1)C1C=CC1