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(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt
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(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt

CAS: 1015073-43-4

Ref. TR-D232080

Estimated delivery in United States, on Monday 14 Dec 2020

Product Information

Name:
(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt
Synonyms:
  • PSI 7411 Triethylammonium Chloride Salt
Description:

Applications (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic Acid Triethylammonium Chloride Salt is an intermediate in the synthesis of (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Triethylammonium Salt (D235370), an impurity of Sofosbuvir (P839640). Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'--fluoro--C-methyluridine-5'-monophosphate.
References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)

Long term storage:
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Chemical properties

Molecular weight:
340.2013765
Formula:
C10H14FN2O8PC6H16ClN
Color/Form:
white solid
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Hazard Info

UN Number:
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