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N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-β]pyridine
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N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-β]pyridine

CAS: 303173-39-9

Ref. TR-D239632

1mg
8,778.00 €
250µg
2,672.00 €
500µg
4,566.00 €
Estimated delivery in United States, on Wednesday 22 Jan 2025

Product Information

Name:
N-(Deoxyguanosin-8-yl)-2-amino-1-(methyl-d3)-6-phenylimidazo[4,5-β]pyridine
Controlled Product
Synonyms:
  • 2'-Deoxy-8-[[1-(methyl-d3)-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl]amino]guanosine
  • dG-C8-PhIP-d3
Description:

Applications The deuterated DNA adduct formed from N-Hydroxy-PHIP. Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).
References Frandsen, H., et al.: Carcinogenesis, 13, 4, 629 (1992), Lin, D., et al.: Chem. Res. Toxicol., 5, 691 (1993), Mizukami, S., et al.: Biochemistry, 45, 2772 (2006),

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:

Chemical properties

Molecular weight:
492.51
Formula:
C23H3H20N9O4
Color/Form:
Neat
InChI:
InChI=1S/C23H23N9O4/c1-31-13-7-12(11-5-3-2-4-6-11)9-25-18(13)27-22(31)30-23-26-17-19(28-21(24)29-20(17)35)32(23)16-8-14(34)15(10-33)36-16/h2-7,9,14-16,33-34H,8,10H2,1H3,(H3,24,28,29,35)(H,25,26,27,30)/t14-,15+,16+/m0/s1/i1D3
InChI key:
InChIKey=UHVGJHQDVDVQHH-UNSNFXJNSA-N
SMILES:
[2H]C([2H])([2H])n1c(Nc2nc3c(=O)[nH]c(N)nc3n2[C@H]2C[C@H](O)[C@@H](CO)O2)nc2ncc(-c3ccccc3)cc21
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EINECS:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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