S-Desethylpiperidino S-(Glycin-N-yl) Vardenafil

CAS: 448184-54-1

Ref. TR-D290975

Product Information

• Name: S-Desethylpiperidino S-(Glycin-N-yl) Vardenafil
• Synonyms: N-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]glycine, Vardenafil Glycene Impurity

Description

Applications S-Desethylpiperidino S-(Glycin-N-yl) Vardenafil is an impurity of Vardenafil (V098001, 2HCl); a selective phosphodiesterase type 5 (PDE5) inhibitor.
References Bischoff, E., et al.: J. Urol., 165, 1316 (2001); Kim, N.N., et al.: Life Sci., 69, 2249 (2001); Kendirci, M., et al.: Expert Opin. Pharmacother., 5, 923 (2004)

• Brand: TRC

Chemical properties

• Molecular weight: 449.48
• Formula: C₁₉H₂₃N₅O₆S
• Color/Form: Off White Solid
• InChI: InChI=1S/C19H23N5O6S/c1-4-6-15-21-11(3)17-19(27)22-18(23-24(15)17)13-9-12(7-8-14(13)30-5-2)31(28,29)20-10-16(25)26/h7-9,20H,4-6,10H2,1-3H3,(H,25,26)(H,22,23,27)
• InChI key: InChIKey=MATHJDYQDWUUSC-UHFFFAOYSA-N
• SMILES: CCCc1nc(C)c2c(=O)nc(-c3cc(S(=O)(=O)NCC(=O)O)ccc3OCC)[nH]n12