Des(methylsulfonyl) Dronedarone Oxalate

CAS: 500791-70-8

Ref. TR-D293600

Product Information

• Name: Des(methylsulfonyl) Dronedarone Oxalate
• Synonyms: (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone Ethanedioate, Dronedarone USP Related Compound B, (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]-methanone ethanedioate, Methanone, (5-amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]-, ethanedioate (1:2)

Description

Impurity Dronedarone USP Related Compound B
Applications Des(methylsulfonyl) Dronedarone Oxalate (Dronedarone USP Related Compound B) is used in the process for preparation of Dronedarone hydrochloride (D679445).
References Mizuno, A., et al.: Chem. Pharm. Bull., 48, 1129 (2000); Dobromir, D., et al.: Lancet, 375, 1212 (2010); Patel, P., et al.: Int. Res. J. Pharm., 2, 59 (2011);

• Brand: TRC

Chemical properties

• Molecular weight: 658.74
• Formula: C₃₄H₄₆N₂O₁₁
• Color/Form: Neat
• InChI: InChI=1S/C30H42N2O3.2C2H2O4/c1-4-7-11-28-29(26-22-24(31)14-17-27(26)35-28)30(33)23-12-15-25(16-13-23)34-21-10-20-32(18-8-5-2)19-9-6-3;2*3-1(4)2(5)6/h12-17,22H,4-11,18-21,31H2,1-3H3;2*(H,3,4)(H,5,6)
• InChI key: InChIKey=DENSIPXSATYPQS-UHFFFAOYSA-N
• SMILES: CCCCc1oc2ccc(N)cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1.O=C(O)C(=O)O.O=C(O)C(=O)O