(aR,​1S,​3S,​4R)​-a,​4-​Dimethyl-​2-​oxo-​3-​(3-​oxobutyl)​-​cyclohexaneacetic Acid

CAS: 173427-03-7

Ref. TR-D476955

Product Information

• Name: (aR,​1S,​3S,​4R)​-a,​4-​Dimethyl-​2-​oxo-​3-​(3-​oxobutyl)​-​cyclohexaneacetic Acid
• Synonyms: Dihydroartemisin Impurity F
• Brand: TRC
• Description: Stability Hygroscopic, Unstable in SolutionApplications (αR,​1S,​3S,​4R)​-α,​4-​Dimethyl-​2-​oxo-​3-​(3-​oxobutyl)​-​cyclohexaneacetic Acid is an impurity of Artemisin (A777500), an active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageReferences Klayman, D.L., et al.: Science, 228, 1049 (1985), Price, R.N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000), Meshnick, S.R., et al.: Int. J., Parasitol., 32, 1655 (2002),

Chemical properties

• Molecular weight: 254.32
• Formula: C₁₄H₂₂O₄
• Color/Form: Neat
• InChI: InChI=1S/C14H22O4/c1-8-4-6-12(10(3)14(17)18)13(16)11(8)7-5-9(2)15/h8,10-12H,4-7H2,1-3H3,(H,17,18)/t8-,10-,11+,12+/m1/s1
• InChI key: InChIKey=SRIAUFRKRAJBGZ-YJQGPUDQSA-N
• SMILES: CC(=O)CC[C@@H]1C(=O)[C@H]([C@@H](C)C(=O)O)CC[C@H]1C