16-Epi-deacetyl-fusidic Acid

CAS: 5951-83-7

Ref. TR-E583000

Product Information

• Name: 16-Epi-deacetyl-fusidic Acid
• Synonyms: 29-Nordammara-17(20),24-dien-21-oic acid, 3,11,16-trihydroxy-, (3a,4a,8a,9ß,11a,13a,14ß,16a,17Z)-, 16-Epifusidic acid, deacetyl- (7CI), 29-Nor-8a,9ß,13a,14ß-dammara-17(20),24-dien-21-oic acid, 3a,11a,16a-trihydroxy-, (Z)- (8CI), (3a,4a,8a,9ß,11a,13a,14ß,16a,17Z)-3,11,16-Trihydroxy-29-nordammara-17(20),24-dien-21-oic acid, 16-Epideacetylfusidic acid, NSC 319631, ent-(17Z)-3ß,11ß,16ß-Trihydroxy-4ß,8,14-trimethyl-18-nor-5ß,10a-cholesta-17(20),24-dien-21-oic acid, 16-epi-Deacetylfusidic acid

Description

Impurity Fusidic Acid EP Impurity I
Applications 16-Epi-deacetyl-fusidic Acid (Fusidic Acid EP Impurity I) is a metabolite of fusidic acid (F865500) which is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells and inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
References Collignon, P., et al.: Int. J. Antimicrob. Agents, 12, S45 (1999), Di Marco, R., et al.: J. Autoimmun., 13, 187 (1999), Price, C.T., et al.: J. Antimicrob., Chemother., 44, 57 (1999),

• Brand: TRC

Chemical properties

• Molecular weight: 474.6725
• Formula: C₂₉H₄₆O₅
• Color/Form: Neat
• InChI: InChI=1S/C29H46O5/c1-16(2)8-7-9-18(26(33)34)24-20-14-22(31)25-27(4)12-11-21(30)17(3)19(27)10-13-28(25,5)29(20,6)15-23(24)32/h8,17,19-23,25,30-32H,7,9-15H2,1-6H3,(H,33,34)/b24-18-/t17-,19-,20-,21+,22+,23+,25-,27-,28-,29-/m0/s1
• InChI key: InChIKey=PWZIHTOPQIWGNP-UHFFFAOYSA-N
• SMILES: Br.CN(C)CCC1=C(c2ccccc2)c2ccccc2C1