4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide
Ref. TR-F593182
25mg
1,530.00€
Product Information
Name:4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide
Controlled Product
Brand:TRC
Description:Applications 4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide is the labeled analogue of 4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide (F593180), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:398.41
Formula:C20H15D3FN5O3
Color/Form:Neat
InChI:InChI=1S/C20H18FN5O3/c1-22-19(27)17-9-12(5-7-24-17)26-16-4-3-13(10-15(16)21)29-14-6-8-25-18(11-14)20(28)23-2/h3-11H,1-2H3,(H,22,27)(H,23,28)(H,24,26)/i1D3
SMILES:c1ccc2c(c1)[I+]c1ccccc1-2
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