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4-Fluoro-1-naphthalenol 1-Formate
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4-Fluoro-1-naphthalenol 1-Formate

CAS: 1000386-62-8

Ref. TR-F593470

Estimated delivery in United States, on Friday 11 Dec 2020

Product Information

Name:
4-Fluoro-1-naphthalenol 1-Formate
Description:

Applications 4-Fluoro-1-naphthalenol 1-Formate is used in the preparation of carboxamide derivatives, naphthalenecarboxamides as inhibitors of CXCR2 for treatment of chemokine-mediated diseases. Also, it is used in the synthesis of 4-Hydroxy Duloxetine (H941800), which is a major metabolite of Duloxetine.
References Hachtel, S., et al.: PCT Int. Appl., 214 (2008); Lantz, R.J., et al.: Drug Dispos. Metab., 31, 1142 (2003), Detke, M., et al.: J. Clin Psy., 63, 308 (2002), Bymaster, F.P., et al.: Bioorg. Med., Chem. Lett., 13, 4477 (2003)

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Chemical properties

Molecular weight:
190.17
Formula:
C11H7FO2
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Hazard Info

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