Product Information
Name:Fursultiamine Hydrochloride
Controlled Product
Synonyms:
- N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-formamide Monohydrochloride
- N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-formamide Monohydrochloride
- TTFD Hydrochloride
- Thiamin Tetrahydrofurfuryl Disulfide Hydrochloride
- Thiamine Tetrahydrofurfuryl Disulfide Hydrochloride
Brand:TRC
Description:
Applications Fursultiamine was synthesized for the purpose of developing forms of thiamine with improved lipophilicity for treating vitamin B1 deficiency. In addition to its clinical indication of avitaminosis, fursultiamine has been studied in clinical trials for Alzheimer's disease and autistic spectrum disorders with positive but modest benefits. It has also been investigated in improving energy metabolism during exercise and reducing exercise-induced fatigue with conflicting results.
References Miura, S.: Nippon Ganka Gakkai Zasshi, 69, 792 (1965); Mimori, Y., et al.: Met. Brain Disease, 11, 89 (1996); Webster, M., et al.: Eur. J. Appl. Physiol. Occup. Physio., 75, 520 (1997)
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Chemical properties
Molecular weight:435.00
Formula:C17H27ClN4O3S2
Color/Form:Neat
InChI:InChI=1S/C17H26N4O3S2.ClH/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18;/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20);1H/b16-12+;
InChI key:InChIKey=OPGOLNDOMSBSCW-PXJKFVASSA-N
SMILES:C/C(=C(\CCO)SSCC1CCCO1)N(C=O)Cc1cnc(C)nc1N.Cl
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