(2S,3R)-Beta-Hydroxyleucine Hydrochloride

CAS: 10148-71-7 1598376-94-3

Ref. TR-H943745

Product Information

• Name: (2S,3R)-Beta-Hydroxyleucine Hydrochloride
• Synonyms: threo-3-Hydroxy-L-leucine Hydrochloride, (2S,3R)-2-Amino-3-hydroxy-4-methylpentanoic acid Hydrochloride, L-threo-beta-Hydroxyleucine Hydrochloride, (3R)-3-Hydroxy-L-leucine Hydrochloride, NSC 524546 Hydrochloride
• CAS: 10148-71-7 1598376-94-3

Description

Applications (2S,3R)-β-Hydroxyleucine is a nonprotein amino acid. (2S,3R)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2S,3R)-β-Hydroxyleucine was effective in inhibiting trypsin and proteinase K of the serine proteases group. (2S,3R)-β-Hydroxyleucine is able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2R,3S)-isomer.
References Hovhannisyan, N. et al.: Amino Acids, 37, 531 (2009); Chitchyan, M.B. et al.: Hayas. Kensab. Hand., 59, 248 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 183.63
• Formula: C₆H₁₄ClNO₃
• Color/Form: White to Off-White Solid
• InChI: InChI=1S/C6H13NO3.ClH/c1-3(2)5(8)4(7)6(9)10;/h3-5,8H,7H2,1-2H3,(H,9,10);1H/t4-,5+;/m0./s1
• InChI key: InChIKey=LJDBRWYTJHYZMD-UYXJWNHNSA-N
• SMILES: CC(C)[C@@H](O)[C@H](N)C(=O)O.Cl